منابع مشابه
Micro-RNAs
Two small temporally regulated RNAs (stRNAs)* of approximately 22 nucleotides regulate timing of gene expression during development of the nematode C. elegans. This regulation occurs at a posttranscriptional, presumably translational, level and is distinct from RNA interference (RNAi). One of the two stRNAs, let-7, as well as its target gene, lin-41, are highly conserved even in humans, suggest...
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“The science of miRNAs and related small RNAs will continue to generate new insights into cancer and possible future treatments” said Nobel Laureate Phillip A. Sharp head of the Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology, Cambridge, at a press conference presenting some of the miRNAs related talks at the recent 101st AACR conference in Washington...
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Micro RNAs (miRNAs) are approximately 22 nucleotide single-stranded noncoding RNA molecules that bind to target messenger RNAs (mRNAs) and silence their expression. This Essay explores the importance of miRNAs in animal development and their possible roles in disease and evolution.
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Gene silencing can occur either at the transcriptional level or post-transcriptional level or both. Many instances of sequence-specific silencing requires small RNAs that can be divided into two major classes: microRNAs (miRNAs) and short-interfering RNAs (siRNAs). miRNAs function in post-transcriptional gene silencing by guiding mRNA degradation or translational repression. Endogenous siRNAs a...
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Article history: Received 2 November 2016 Accepted 2 November 2016 Available online 8 November 2016 and development has become an intense area of research (Zhu et al., 2014), the role of host miRNAs in shaping immune responses against these parasites has been poorly characterized. In a previous study He and coworkers performed a miRNA microarray on livers from S. japonicum-infected mice and ide...
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ژورنال
عنوان ژورنال: Journal of Evolution of Medical and Dental Sciences
سال: 2019
ISSN: 2278-4748,2278-4802
DOI: 10.14260/jemds/2019/634